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DEPARTMENT OF HEALTH & HUMAN SERVICES - Public Health Service National Institutes of Health The lack of connection between the human data and the experimental data (animal and mechanistic) severely complicates the interpretation of these results. The human data are in the "right" species, are tied to "real life" exposures and show some consistency that is difficult to ignore. This assessment is tempered by the observation that given the weak magnitude of these increased risks, some other factor or common source of error could explain these findings. However, no consistent explanation other than exposure to ELF-EMF has been identified. Epidemiological studies have serious limitations in their ability to demonstrate a cause and effect relationship whereas laboratory studies, by design, can clearly show that cause and effect are possible. Virtually all of the laboratory evidence in animals and humans and most of the mechanistic work done in cells fail to support a causal relationship between exposure to ELF-EMF at environmental levels and changes in biological function or disease status. The lack of consistent, positive findings in animal or mechanistic studies weakens the belief that this association is actually due to ELF-EMF, but it cannot completely discount the epidemiological findings. The NIEHS concludes that ELF-EMF exposure cannot be recognized at this time as entirely safe because of weak scientific evidence that exposure may pose a leukemia hazard. In my opinion, the conclusion of this report is insufficient to warrant aggressive regulatory concern. However, because virtually everyone in the United States uses electricity and therefore is routinely exposed to ELF-EMF, passive regulatory action is warranted such as a continued emphasis on educating both the public and the regulated community on means aimed at reducing exposures. The NIEHS does not believe that other cancers or non-cancer health outcomes provide sufficient evidence of a risk to currently warrant concern. The interaction of humans with ELF-EMF is complicated and will undoubtedly continue to be an area of public concern. The EMF-RAPID Program successfully contributed to the scientific knowledge on ELF-EMF through its support of high quality, hypothesis-based research. While some questions were answered, others remain. Building upon the knowledge base developed under the EMF-RAPID Program, meritorious research on ELF-EMF through carefully designed, hypothesis-driven studies should continue for areas warranting fundamental study including leukemia. Recent research in two areas, neurodegenerative diseases and cardiac diseases associated with heart rate variability, have identified some interesting and novel findings for which further study is ongoing. Advocacy groups have opposing views concerning the health effects of ELF-EMF. Some advocacy groups want complete exoneration and others want a more serious indictment. Our conclusions are prudent and consistent with the scientific data. I am satisfied with the report and believe it provides a pragmatic, scientifically-driven basis for any further regulatory review. I am pleased to transmit this report to the U.S. Congress. Sincerely, Kenneth Olden, Ph.D.
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